Work from the Chen group at Shanghai University published in Microchimica Acta described the development of a surface plasmon resonance (SPR) sensor using pyridinium porphyrin-mediated gold nanoparticle composites to amplify SPR signal when detecting B-type natriuretic peptide (BNP). The determination range for the sensor was shown to be broad and the experimental execution simple and easily performed. Thanks for

Recent work from the Mourzina group at Institute of Complex Systems-8 (Bioelectronics), Germany was published in Journal of Electroanalytical Chemistry presenting electrochemical properties and biomimetic activity of a series of water-soluble meso-substituted Mn(III) porphyrin complexes in the electrocatalytic reduction of hydrogen peroxide in aqueous solutions. The results of this study demonstrate that the electrochemical systems

Olga A. Ryazanova, et. al. recently reported the synthesis and evaluation of a pheophorbide a phenazinium dye conjugate which is effective as a probe for G-quadruplex structures of nucleic acids. The fluorescence band of the aminophenazinium dye overlaps with the absorption band of pheophorbide a , resulting in the quenching of the phenazinium moiety by

Recent work from the Lannutti group at the Ohio State University was published in Journal of Sensors and Actuators B: Chemical, evaluating compositional parameters and other factors governing fiber design appropriate to long-term sensor applications. These nanofibers contain an oxygen-sensitive palladium (II) porphyrin species within a polysulfone core; an outer polycaprolactone shell protects the core from the surrounding environment. This study provides a detailed

Recent work at Shanghai University by the Chen group was published in Microchimica Acta reporting a surface plasmon resonance biosensor for the determination of brain natriuretic peptide. Detection was accomplished by binding of the peptide to an amine functionalized aptamer probe. Pyridinium porphyrin-mediated Au nanoparticle composites were used to amplify the SPR signal. Thanks for

Recent work from the Farag group at the Cairo University, Giza, Egypt was published in Journal of Photodiagnosis and Photodynamic Therapy reassuring the usage of Meso-tetrakis(N-methyl-4-pyridyl)porphyrin (TMPyP) as photosensitizing agent by loading in ethosomes. TMPyP (a photosensitizer) was considered for the topical treatment of subcutaneous tumors. The hydrophilicity of TMPyP hampers its skin penetration. TMPyP was formulated in nanovesicles called ethosomes to overcome the skin barrier and allow for its transdermal delivery.  Thanks for using our Meso-tetrakis(N-methyl-4-pyridyl)porphyrin (TMPyP), T40125.  

Recent work from the Kurtz group at University of Texas was published in Biochemistry journal, presenting X-ray crystal structure of ZnPP-Bfr as well as the photophysical properties of the iron-loaded ZnPP-Bfr to better understand the process of photosensitized reductive iron release. The crystal structure of ZnPP-Bfr shows a unique six-coordinate zinc in the ZnPP with two axial methionine sulfur ligands.  Thanks for using our Protoporphyrin IX, (P562-9). 

Recent work from the Doctorovich group at the University of Buenos Aires published in JACS identified the first biomimetic water-soluble FeII-porphyrin nitroxyl complexes. A pKa was calculated for the complex and reaction kinetics measured. DFT calculations implied the formation of a phlorin radical intermediate for the investigated reaction. Thanks for using our meso-tetra(4-sulfonatophenyl)porphine, T40699. 

Recent work from the Vesselli group at the University of Trieste published in Topics in Catalysis demonstrated both experimental and computational results for the metal-organic framework (MOF) structure of 5,10,15,20-tetra(4-pyridyl)21H,23H-porphyrin cobalt(III) chloride assembled on a Au(111) surface. The generated MOF was able to mimic O2 stabilization and activation mechanisms typically observed in proteins and enzymes. Thanks for using our cobalt tetrapyridylporphyrin, T40892.