Recent work from the MacMillan group at Princeton University was published in Science Journal presenting a biomimetic SH2 cross-coupling mechanism for quaternary sp3-carbon formation. This study examined the cross-coupling between tertiary redox-active esters and primary alkyl bromides in the presence of Fe(OEP)Cl as an effective SH2 catalyst, in tandem with Iridium based photocatalyst and the […]
Electrochemical properties and biomimetic activity of water-soluble meso-substituted Mn(III) porphyrin complexes in the electrocatalytic reduction of hydrogen peroxide
Recent work from the Mourzina group at Institute of Complex Systems-8 (Bioelectronics), Germany was published in Journal of Electroanalytical Chemistry presenting electrochemical properties and biomimetic activity of a series of water-soluble meso-substituted Mn(III) porphyrin complexes in the electrocatalytic reduction of hydrogen peroxide in aqueous solutions. The results of this study demonstrate that the electrochemical systems
Recent work from the Lannutti group at the Ohio State University was published in Journal of Sensors and Actuators B: Chemical, evaluating compositional parameters and other factors governing fiber design appropriate to long-term sensor applications. These nanofibers contain an oxygen-sensitive palladium (II) porphyrin species within a polysulfone core; an outer polycaprolactone shell protects the core from the surrounding environment. This study provides a detailed
Topical photodynamic therapy of tumor bearing mice with meso-tetrakis (N-methyl-4-pyridyl) porphyrin loaded in ethosomes.
Recent work from the Farag group at the Cairo University, Giza, Egypt was published in Journal of Photodiagnosis and Photodynamic Therapy reassuring the usage of Meso-tetrakis(N-methyl-4-pyridyl)porphyrin (TMPyP) as photosensitizing agent by loading in ethosomes. TMPyP (a photosensitizer) was considered for the topical treatment of subcutaneous tumors. The hydrophilicity of TMPyP hampers its skin penetration. TMPyP was formulated in nanovesicles called ethosomes to overcome the skin barrier and allow for its transdermal delivery. Thanks for using our Meso-tetrakis(N-methyl-4-pyridyl)porphyrin (TMPyP), T40125.
Structure of a Zinc Porphyrin-Substituted Bacterioferritin and Photophysical Properties of Iron Reduction
Recent work from the Kurtz group at University of Texas was published in Biochemistry journal, presenting X-ray crystal structure of ZnPP-Bfr as well as the photophysical properties of the iron-loaded ZnPP-Bfr to better understand the process of photosensitized reductive iron release. The crystal structure of ZnPP-Bfr shows a unique six-coordinate zinc in the ZnPP with two axial methionine sulfur ligands. Thanks for using our Protoporphyrin IX, (P562-9).