Zn(II) meso-Tetra (N-methyl-4-pyridyl) Porphine Tetrachloride

Zn(II) meso-Tetra (N-methyl-4-pyridyl) Porphine Tetrachloride CAS: 28850-44-4 MDL: MFCD00274280

SDS

Molecular weight: 884.031

Molecular Formula: C₄₄H₃₆Cl₄N₈Zn

CAS Number: 28850-44-4

Storage: Store at room temperature, protect from light.

Synonyms: {4,4′,4”,4”’-(5,10,15,20-Porphyrintetrayl-κ²N²¹,N²³)tetrakis[1-methylpyridiniumato(2-)]}zinc(4+) tetrachloride, {4,4′,4”,4”’-(5,10,15,20-Porphyrintetrayl-κ²N²¹,N²³)tetrakis[1-methylpyridiniumato(2-)]}zink(4+)tetrachlorid, Tétrachlorure de {4,4′,4”,4”’-(5,10,15,20-porphyrinetétrayl-κ²N²¹,N²³)tétrakis[1-méthylpyridiniumato(2-)]}zinc(4+), Zinc(4+), [4,4′,4”,4”’-(21H,23H-porphine-5,10,15,20-tetrayl-κN²¹,κN²³)tetrakis[1-methylpyridiniumato](2-)]-, chloride (1:4), 28850-44-4, MFCD00274280, Zinc 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine tetrakis(methochloride), Zn(II) meso-Tetra (N-methyl-4-pyridyl) Porphine Tetrachloride, ZnTMPyP4.

Background: Zn(II) meso-Tetra (N-methyl-4-pyridyl) Porphine Tetrachloride is a synthetic porphyrin specialty chemical manufactured by Frontier Specialty Chemicals. Zn(II) meso-Tetra (N-methyl-4-pyridyl) Porphine Tetrachloride was used for the photoinduced electron/energy transfer – reversible addition–fragmentation chain transfer (PET-RAFT) forced-gradient copolymerisation in water under orange light irradiation for the assembly of polymeric nanoparticles.^1-4 The triplet excited state of Zn(II) meso-Tetra (N-methyl-4-pyridyl) Porphine Tetrachloride was used to probe the binding interaction of this porphyrin to G-quadruplex DNA, providing insight into the design of anti-cancer drugs targeting G-quadruplex.⁵

References:

1.) Xu, et al. Forced gradient copolymerisation: a simplified approach for polymerisation-induced self-assembly. Polym. Chem., 2021, 12, 57-68. 10.1039/D0PY00889C

2.) Corrigan, et al. Mediating Reaction Orthogonality in Polymer and Materials Science. Angew. Chemie Int.ed. Volume 60, Issue 4, January 25, 2021, Pages 1748-1781. https://doi.org/10.1002/anie.201912001

3.) Fortenberry, et al. Considerations for and Applications of Aqueous RAFT Polymerization. RAFT Polymerization: Methods, Synthesis and Applications, Volume 2. Chapter 14. https://doi.org/10.1002/9783527821358.ch14

4.) Xu, et al. Gradient Polymerization–Induced Self-Assembly: A One-Step Approach. Macromolecular Rapid Communications. Volume 41, Issue 1, Special Issue: 100 Years of Macromolecular Chemistry, January 2020, 1900493. https://doi.org/10.1002/marc.201900493

5.) Yao, et al. Interaction between G-Quadruplex and Zinc Cationic Porphyrin: The Role of the Axial Water. Scientific Reports volume 7, Article number: 10951 (2017). https://doi.org/10.1038/s41598-017-11413-8