Mesoporphyrin IX dihydrochloride 8,13-Bis(ethyl)-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid dihydrochloride CAS: 68938-72-7 MDL: MFCD00136049

Molecular weight: 639.6  g/mol

Molecular Formula: C₃₄H₃₈N₄O₄ 2 HCl

CAS Number:  CAS: 68938-72-7

Storage: Store at room temperature, protect from light.

Synonyms: Mesoporphyrin IX, MESOPORPHYRIN, MPIX, 493-90-3

Mesoporphyrin IX, dihydrochloride, 7,12-Diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid, 68938-72-7, 7,12-diethyl-3,8,13,17-tetramethyl-2,18, Porphinedipropionic acid, 21H,23H-Porphine-2,18-dipropanoicacid, 7,12-diethyl-3,8,13,17-tetramethyl-, hydrochloride (1:2), 7,12-Diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid, mesoprotoporphyrin, EINECS 207-782-4, 3,3′-(7,12-diethyl-3,8,13,17, tetramethylporphyrin-2,18-diyl)dipropanoic acid, SCHEMBL314687, CHEMBL276179 

Field of Interest: Natural Porphyrin, Catalyst, Radical Scavenger, Photosensitizers, Anti-microbial Agents, Dye Sensitized Solar Cells

Background: Mesoporphyrin IX dihydrochloride is a natural product and specialty chemical which displays antimicrobial properties.¹ Mesoporphyrin IX dihydrochloride exhibits photosensitizer properties.² Mesoporphyrin IX dihydrochloride is structurally similar to protoporphyrin IX, but is chemically more stable due to the lack of the highly chemically reactive vinyl groups. Peptide conjugates of mesoporphyrin IX targeting EGFR have been described.³ A mesoporphyrin IX functionalized PEG was synthesized and demonstrated oxygen phosensitization.⁴ Mesoporphyrin IX has been used for the construction of highly efficient dye sensitized solar cells.⁵ The photophysics of mesoporphyrin IX in solution and as a sol-gel have been reported.⁶

 References:   

1.) Jegessar, et al. Mesoporphyrin (ix) Dihydrochloride as a Non-Selective Antimicrobial Agent J Pure Appl Microbiol. 2010;4(2):507-512.

2.) Herenyi, et al. Location of mesoporphyrin in liposomes determined by site-selective fluorescence spectroscopy. J. Phys. Chem. B 2009, 113, 21, 7716–7724.

3.) Fontenot, et al. Targeting of the epidermal growth factor receptor with mesoporphyrin IX-peptide conjugates. Journal of Porphyrins and PhthalocyaninesVol. 20, No. 01 n04, pp. 352-366 (2016)

4.) Abos, et al. Polymer bound pyrrole compounds, IX. Photophysical and singlet molecular oxygen photosensitizing properties of mesoporphyrin IX covalently bound to a low molecular weigh polyethylene glycol. Journal of Photochemistry and Photobiology B: Biology, 41, 1-2, 1997, 53-59. 

5.) Lopez-Garcia, et al. Electrophoretically-Assisted Deposition of Mesoporphyrin IX on Nanoparticulate TiO2 Films for Constructing Efficient Dye-Sensitized Solar Cells. Journal of The Electrochemical Society, Volume 158, Number 6

6.) Pereira, et. al. Photophysics of mesoporphyrin IX in solution and confined in sol-gel-derived matrices. Journal of Photochemistry and Photobiology A: Chemistry Volume 172, Issue 1, 15 May 2005, Pages 7-17

 

 

 

 

 

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