meso-Tetra(m-hydroxyphenyl)porphine

meso-Tetra(m-hydroxyphenyl)porphine 5,10,15,20-Tetrakis(3-hydroxyphenyl)-21H,23H-porphine CAS: 22112-79-4 MDL: MFCD06657911

Molecular weight: 678.74 g/mol

Molecular Formula: C₄₄H₃₀N₄O₄

CAS Number: 22112-79-4

Storage: Store at room temperature, protect from light.

Synonyms: 3,3′,3”,3”’-(5,10,15,20-Porphyrinetétrayl)tetraphénol, 3,3′,3”,3”’-(5,10,15,20-Porphyrintetrayl)tetraphenol, 3,3′,3”,3”’-(5,10,15,20-Porphyrintetrayl)tetraphenol, 3,3′,3”,3”’-Porphyrin-5,10,15,20-tetrayltetraphenol, 5,10,15,20-tetrakis(3-hydroxyphenyl)porphyrin, Phenol, 3,3′,3”,3′”-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-, 22112-79-4, 3,3′,3”,3”’-(21H,23H-Porphine-5,10,15,20-tetrayl)tetrakisphenol, 5,10,15,20-tetra(3-hydroxyphenyl)porphyrin, 5,10,15,20-Tetrakis(3-hydroxyphenyl)-21H,23H-porphine, 5,10,15,20-tetrakis(3-hydroxyphenyl)-porphyrin, meso-5,10,15,20-tetra(3-hydroxyphenyl)porphine, meso-tetra(m-hydroxylphenyl)porphine, meso-Tetra(m-hydroxyphenyl)porphine, meta-tetrahydroxyphenylporphyrin, MFCD06657911, porphine, 5,10,15,20-tetrakis(3-hydroxyphenyl)-, Tetra(3-hydroxyphenyl)porphyrin

Fields of Interest: Synthetic Porphyrins, Photosensitizers

Background: meso-Tetra(m-hydroxyphenyl)porphine is a synthetic porphyrin specialty chemical manufactured by Frontier Specialty Chemicals.

References:

1.) Shirakawa, et al. Hydrogen-bond-assisted control of H versus J aggregation mode of porphyrins stacks in an organogel system. Journal of Organic Chemistry, 2003, vol. 68, # 13, p. 5037 – 5044. https://doi.org/10.1021/jo0341822

2.) Bonnett, et al. Photophysical properties of 5,10,15,20-tetrakis(m-hydroxyphenyl)-porphyrin (m-THPP), 5,10,15,20-tetrakis(m-hydroxyphenyl)chlorin (m-THPC) and 5,10,15,20-tetrakis(m-hydroxyphenyl)bacteriochlorin (m-THPBC): A comparative study. Journal of the Chemical Society. Perkin Transactions 2 (2001), 1999, # 2, p. 325 – 328. https://doi.org/10.1039/A805328F

3.) Banfi, et al. Photodynamic effects of porphyrin and chlorin photosensitizers in human colon adenocarcinoma cells. Bioorganic and Medicinal Chemistry, 2004, vol. 12, # 18, p. 4853 – 4860. https://doi.org/10.1016/j.bmc.2004.07.011

4.) Arnaut, et al. Photodynamic therapy efficacy enhanced by dynamics: The role of charge transfer and photostability in the selection of photosensitizers. Chemistry – A European Journal, 2014, vol. 20, # 18, p. 5346 – 5357. https://doi.org/10.1002/chem.201304202

5.) Kralova, et al. Glycol porphyrin derivatives as potent photodynamic inducers of apoptosis in tumor cells. Journal of Medicinal Chemistry, 2008, vol. 51, # 19, p. 5964 – 5973. https://doi.org/10.1021/jm8002119

6.) Bonnett, et al. Photobleaching of Compounds of the 5,10,15,20-Tetrakis(m-hydroxyphenyl)-porphyrin Series (m-THPP, m-THPC, and m-THPBC). Organic Letters, 2002, vol. 4, # 12, p. 2013 – 2016. https://doi.org/10.1021/ol025842c