Chlorin e4 CAS: 550-52-7 MDL: MFCD10566749
Molecular weight: 552.7 g/mol
Molecular Formula: C33H36N4O4Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â
CAS Number: Â 550-52-7
Storage: Store at –20 °C, protect from light.
Synonyms: SCHEMBL14039063, 21H,23H-PORPHINE-7-PROPANOIC ACID, 3-CARBOXY-13-ETHENYL-18-ETHYL-7,8-DIHYDRO-2,5,8,12,17-PENTAMETHYL-, (7S,8S)-, J2.069.722I, (7S,8S)-3-Carboxy-13-ethenyl-18-ethyl-7,8-dihydro-2,5,8,12,17-pentamethyl-21H,23H-porphyrin-7-propanoic acid.
Alternative Chemical Names
(17S,18S)-18-(2-Carboxyethyl)-7-ethyl-3,8,13,17,20-pentamethyl-12-vinyl-17,18-dihydro-2-porphyrincarbonsäure, (17S,18S)-18-(2-Carboxyethyl)-7-ethyl-3,8,13,17,20-pentamethyl-12-vinyl-17,18-dihydro-2-porphyrincarboxylic acid, 21H,23H-Porphine-7-propanoic acid, 3-carboxy-13-ethenyl-18-ethyl-7,8-dihydro-2,5,8,12,17-pentamethyl-, (7S,8S)-, Acide (17S,18S)-18-(2-carboxyéthyl)-7-éthyl-3,8,13,17,20-pentaméthyl-12-vinyl-17,18-dihydro-2-porphyrinecarboxylique, (7S,8S)-3-carboxy-13-ethenyl-18-ethyl-7,8-dihydro-2,5,8,12,17-pentamethyl-21H,23H-Porphine-7-propanoic acid, 21H,23H-Porphine-7-propanoic acid,3-carboxy-13-ethenyl-18-ethyl-7,8-dihydro-2,5,8,12,17-pentamethyl-,(7s,8s)-
Field of Interest: Natural Products Synthesis, Inflammation Activity, Solar Cells
Background: Chlorin e4 is a porphyrin based natural product and fine chemical that possesses photophysical properties while cytoprotective in mammalian cells. 1,2 This compound is found in chlorophyllin extracts, and may add to its chemoprevention properties, and have high membrane affinity compared to porphyrins.3, 4
References:Â
1.) Wang, Xiao-Feng; Kitao, Osamu, Natural chlorophyll-related porphyrins and chlorins for dye-sensitized solar cells, Molecules (2012), 17, 4484-4497.
2.) Fahey Jed W; Stephenson Katherine K; Dinkova-Kostova Albena T; Egner Patricia A; Kensler Thomas W; Talalay Paul, Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes , Carcinogenesis (2005), 26(7), 1247-55.
3.) Egner, Patricia A.; Stansbury, Kevin H.; Snyder, Edward P.; Rogers, Mark E.; Hintz, Paul A.; Kensler, Thomas W., Identification and Characterization of Chlorin e4 Ethyl Ester in Sera of Individuals Participating in the Chlorophyllin Chemoprevention Trial, Chemical Research in Toxicology (2000), 13(9), 900-906.
4.)Â Vermathen, Martina; Marzorati, Mattia; Bigler, Peter, Self-Assembling Properties of Porphyrinic Photosensitizers and Their Effect on Membrane Interactions Probed by NMR Spectroscopy, Â Journal of Physical Chemistry B (2013), 117(23), 6990-7001.
