Name: N-(3-aminopropyl)-2-pyrrolidinone
Molecular Formula: C7H14N2O
CAS#: 7663-77-6
SMILES: O=C1N(CCCN)CCC1
MDL#: MFCD00003201
Catalog#: A35206
Molecular weight: 142.2 g/mol
Other names:
- 1-(3-Aminopropyl)-2-pyrrolidone
Fields of Interest: Organic Synthesis
Background & Applications:
N-(3-aminopropyl)-2-pyrrolidinone is a bifunctional pyrrolidone derivative combining a polar lactam ring with a reactive primary amine. This structure gives it high water solubility, strong hydrogen-bonding capacity, and chemical reactivity, making it primarily useful as an intermediate rather than a finished product. Its design is related to common industrial pyrrolidones (e.g., NMP), but the added amine enables covalent bonding and further functionalization. It can also be used as a precursor for bioactive heterocycles and a building block for drug candidates.
Industrially, it is used mainly in polymer, resin, and coating applications as a reactive intermediate, adhesion promoter, or functional additive, where it improves polarity, compatibility, and surface adhesion. It also serves as a fine chemical and pharmaceutical intermediate, and in specialty formulations (including agrochemical additives) where enhanced solubility and reactivity are desired.
Appearance: Pale orange/yellow viscous liquid
Purity: 96%
Storage: Room Temperature
Solubility: Methylene chloride and most organic solvents
Literature: Patent: WO2003/105779,2003,A2