Name: N-(2-Methoxyethyl)octadecan-1-amine
Molecular Formula: C21H45NO
CAS#: 2484919-96-0
SMILES: CCCCCCCCCCCCCCCCCCNCCOC
MDL#: MFCD32869471
Catalog#: AMTGC664-MO20
Molecular weight: 327.60 g/mol
Other names:
- N-(2-Methoxyethyl)octadecylamine
- Methoxyethyl octadecylamine
- C18 secondary amine (methoxyethyl)
Fields of Interest: materials science, surface modification, and formulation chemistry
Background & Applications:
Background
N-(2-Methoxyethyl)octadecan-1-amine is a long-chain amine-functionalized ether derivative featuring a secondary amine linked to a hydrophobic octadecyl (C18) alkyl chain and a short methoxyethyl group. This structure combines a lipophilic tail with a polar ether-linked segment, providing amphiphilic character and compatibility with both organic and limited aqueous environments. The secondary amine offers tunable basicity and reactivity toward electrophiles, while the long alkyl chain promotes interactions with lipid environments and hydrophobic surfaces. This compound serves as a versatile building block within a broader portfolio of functionalized amines and linker molecules designed for controlled molecular modification and surface-active applications.
Applications
N-(2-Methoxyethyl)octadecan-1-amine is commonly used in materials science, surface modification, and formulation chemistry where amphiphilic structure and amine functionality are desired. Typical uses include incorporation into surfactants and coatings, modification of nanoparticles or surfaces to introduce hydrophobic–hydrophilic balance, and preparation of intermediates for specialty chemicals and lipid-based systems. The combination of a hydrophobic C18 chain and a functional secondary amine makes this compound particularly useful in applications involving self-assembly, emulsification, or interaction with biological membranes. As part of a diverse functionalized chemical product line, this compound supports modular design strategies in advanced materials, formulations, and specialty synthesis.
Appearance: Yellow solid
Purity: 97%
Storage: Room Temp
Solubility: Dichloromethane, Chloroform
Literature:
- Bioconjugate Chemistry, 2013, vol. 24, # 9, p. 1543 – 1551