Name: 5,5-difluoro-2,8-diiodo-1,3,7,9-tetramethyl-10-phenyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2′,1′-f][1,3,2]diazaborinine
Molecular Formula: C19H17BF2I2N2
CAS#: 1083009-44-2
SMILES: CC1=C(I)C(C)=[N+](C1=C2C3=CC=CC=C3)[B-](F)(F)N4C2=C(C)C(I)=C4C
MDL#: MFCD32856217
Catalog#: D36247
Molecular weight: 575.96 g/mol
Other names:
- 1083009-44-2
- 2,6-diiodo-4,4-difluoro-1,3,5,7-tetramethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene
- 8-Phenyl-2,6-diiodo-1,3,5,7-tetramethyl BODIPY
Fields of Interest: photodynamic therapy, drug discovery, fluorescent probe development, bioimaging, and advanced materials research
Background & Applications:
5,5-Difluoro-2,8-diiodo-1,3,7,9-tetramethyl-10-phenyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2′,1′-f][1,3,2]diazaborinine (CAS 1083009-44-2) is a specialized BODIPY dye intermediate used in drug discovery, fluorescent probe development, bioimaging, and advanced materials research. Identified by CAS 1083009-44-2, this halogenated boron-dipyrromethene (BODIPY) compound is valued for its highly functionalized fluorescent core and its utility in the synthesis of tailored dyes, labeled molecules, and imaging tools for pharmaceutical and life science research.
In drug discovery and chemical biology, BODIPY dyes are widely used in the development of fluorescent probes, labeled ligands, assay reagents, and bioactive conjugates. The diiodo substitution pattern in this compound provides useful reactive sites for cross-coupling, derivatization, and scaffold diversification, enabling researchers to prepare customized BODIPY-based molecules for target visualization, screening assays, uptake studies, and structure-activity investigations. This makes the compound especially useful for medicinal chemistry and translational research teams seeking robust fluorescent building blocks for discovery workflows.
Beyond pharmaceutical research, this BODIPY intermediate is also well suited for fluorescence imaging, sensor development, diagnostics research, photophysical studies, and optoelectronic materials design. Its boron-centered dye framework supports the development of novel fluorescent compounds with tunable properties for use in both academic and industrial R&D.
Appearance: red orange solid
Purity: 96%
Storage: Store at 3-5 °C
Solubility: DCM
Literature:
- Zou J, et al., BODIPY Derivatives for Photodynamic Therapy: Influence of Configuration versus Heavy Atom Effect. ACS Appl Mater Interfaces. 2017 Sep 27;9(38):32475-32481. doi: 10.1021/acsami.7b07569