4-[3-(2-Methoxyethoxy)propylamino]-4-oxobutanoic acid (99%)

Name: 4-[3-(2-Methoxyethoxy)propylamino]-4-oxobutanoic acid 

Molecular Formula: C10H19NO5 

CAS#: 1184419-48-4 

SMILES: COCCOCCCNC(CCC(O)=O)=O 

MDL#: none found 

Catalog#: AMTGC1256-PA24 

Molecular weight: 233.26 g/mol 

Other names: 

• N-[3-(2-Methoxyethoxy)propyl]succinamic acid  

• 4-Oxo-4-[[3-(2-methoxyethoxy)propyl]amino]butanoic acid 

• Methoxyethoxypropyl succinamic acid  

• PEG-like succinamic acid linker  

• Carboxylic acid ether linker 

Fields of Interest: bioconjugation, materials science, and specialty chemical synthesis 

Background & Applications:  

Background 

4-[3-(2-Methoxyethoxy)propylamino]-4-oxobutanoic acid is a multifunctional amide-linked ether derivative featuring a methoxyethoxypropyl chain attached to a terminal succinamic acid moiety. The ether-containing segment provides hydrophilicity, flexibility, and compatibility with aqueous and organic systems, while the terminal carboxylic acid enables straightforward coupling to amines and other nucleophiles through standard activation chemistry. The internal amide linkage contributes stability and polarity, making the compound a useful intermediate for modular molecular assembly. This compound serves as a versatile building block within a broader portfolio of functionalized linkers and PEG-like intermediates designed for controlled conjugation and solubility enhancement. 

Applications 

4-[3-(2-Methoxyethoxy)propylamino]-4-oxobutanoic acid is commonly used in bioconjugation, materials science, and specialty chemical synthesis applications where hydrophilic spacing and terminal carboxylic acid functionality are required. Typical uses include preparation of amide-linked conjugates, incorporation into polymers or surface-modified materials, and synthesis of pharmaceutical or biomaterials intermediates. The combination of a hydrophilic ether chain and a reactive carboxylic acid makes this compound useful for introducing flexible, water-compatible linkers into multifunctional systems. As part of a comprehensive functionalized chemical product line, this compound supports modular design strategies in diagnostics, advanced materials development, and medicinal chemistry. 

Appearance: Pale-yellow, viscous liquid 

Purity: 99% 

Storage: Room Temp 

Solubility: Dichloromethane, Chloroform, Methanol 

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