Name: 1,3,5,7-Tetramethyl-8-phenyl-4,4-difluoroboradiazaindacene
Molecular Formula: C19H19BF2N2
CAS#: 194235-40-0
SMILES: CC1=CC(C)=[N+](C1=C2C3=CC=CC=C3)[B-](F)(F)N4C2=C(C)C=C4C
MDL#: MFCD28137455
Catalog#: T36244
Molecular weight: 324.18 g/mol
Other names:
- BODIPY dye
- Boron dipyrromethene fluorophore
- Difluoro{2-[(3,5-dimethyl-2H-pyrrol-2-ylidene-N)phenylmethyl]-3,5-dimethyl-1H-pyrrolato-N}boron
Fields of Interest: Bodipy dyes, Fluorescent probes, drug discovery, bioimaging, assay development, OLED development
Background & Applications:
1,3,5,7-Tetramethyl-8-phenyl-4,4-difluoroboradiazaindacene is a versatile BODIPY dye used in drug discovery, bioimaging, assay development, and fluorescence-based research. Identified by CAS 194235-40-0, this boron-dipyrromethene (BODIPY) fluorophore is valued for its strong fluorescence, well-defined dye scaffold, and utility in the development of probes, labeled molecules, and analytical tools for pharmaceutical, life science, and specialty chemical applications.
In drug discovery and chemical biology, this compound is useful as a BODIPY fluorescent scaffold for the preparation of probes, conjugates, assay reagents, and labeled ligands used in screening, target engagement studies, cellular imaging, and fluorescence-based workflow development. BODIPY dyes are widely used to help researchers visualize molecular interactions, monitor compound behavior, and support discovery programs that rely on sensitive optical readouts. This makes 1,3,5,7-Tetramethyl-8-phenyl-4,4-difluoroboradiazaindacene a valuable choice for medicinal chemistry, translational research, and broader life science workflows requiring reliable fluorescent labeling technologies.
Beyond pharmaceutical research, this BODIPY dye is also well suited for bioimaging, sensor development, diagnostics research, analytical chemistry, and photophysical studies. Its boron-containing dye framework supports the development of customized fluorescent systems for use in both academic and industrial R&D, including applications involving imaging tools, fluorescence methods, and advanced labeled compounds.
As part of a broader portfolio of BODIPY dyes and boron-containing fluorophores, 1,3,5,7-Tetramethyl-8-phenyl-4,4-difluoroboradiazaindacene offers researchers a versatile platform for drug discovery, imaging, assay development, and specialty chemical research.
BODIPY dyes are widely used for labeling and tracking biomolecules such as proteins, nucleotides, oligonucleotides, and carbohydrates. These fluorescent conjugates enable visualization of cellular structures, analysis of molecular interactions, and investigation of membrane dynamics and signaling pathways. BODIPY derivatives are also important in imaging applications, where they serve as fluorescent probes, making them highly useful for live-cell imaging and diagnostic studies. In addition, they are used as modified dyes in the development of organic light-emitting diodes (OLEDs).
Appearance: Orange solid
Purity: 95.6%
Storage:
Solubility: CH2Cl2, CHCl3
Literature:
- DOI https://doi.org/10.1039/C8TC06421K
- DOI https://doi.org/10.1039/C4TC00720D