1-(4-Bromopyridin-2-yl)ethanone

1-(4-Bromopyridin-2-yl)ethanone 2-Acetyl-4-bromopyridine CAS: 1060805-69-7 MDL: MFCD13189212

Molecular weight: 200.03    g/mol

Molecular Formula: C₇H₆BrNO

CAS Number: 060805-69-7

Storage: Store at 2-8 C^o, under dry conditions.

Synonyms:   None found

Application: Synthesis building block, nitrogen heterocycle, bromine reactions, ketone reactions

1-(4-Bromopyridin-2-yl)ethanone is a synthetic specialty chemical useful in the synthesis of pharmaceuticals and specialty organic chemicals.

Selected References:

1.) Becica, Joseph, Damian P. Hruszkewycz, Janelle E. Steves, Jennifer M. Elward, David C. Leitch, and Graham E. Dobereiner.   Adbippyphos Promotes Pd-Catalyzed C-N Coupling between Weakly Nucleophilic Sulfonamides and Heteroaryl Halides.   ChemRxiv, no.  (2019): 1–6.

2.) Joseph Becica, Damian P. Hruszkewycz, Janelle E. Steves, Jennifer M. Elward, David C. Leitch, and Graham E. Dobereiner   High-Throughput Discovery and Evaluation of a General Catalytic Method for N-Arylation of Weakly Nucleophilic Sulfonamides.   Organic Letters 21, no.  (2019): 8981–86. https://doi.org/10.1021/acs.orglett.9b03380.

3.) Fosso, Marina Y., Harry III LeVine, Keith D. Green, Oleg V. Tsodikov, and Sylvie. Garneau-Tsodikova.   Effects of Structural Modifications on the Metal Binding, Anti-Amyloid Activity, and Cholinesterase Inhibitory Activity of Chalcones.   Organic & Biomolecular Chemistry 13, no.  (2015): 9418–26. https://doi.org/10.1039/C5OB01478F.

4.) Ozawa, Hironobu, Takahiro Kuroda, Shohei Harada, and Hironori. Arakawa.   Efficient Ruthenium Sensitizer with a Terpyridine Ligand Having a Hexylthiophene Unit for Dye-Sensitized Solar Cells: Effects of the Substituent Position on the Solar Cell Performance.   European Journal of Inorganic Chemistry 2014, no.  (2014): 4734–39. https://doi.org/10.1002/ejic.201402530.

5.) Ozawa, Hironobu, Yasuyuki Yamamoto, Hiroki Kawaguchi, Ryosuke Shimizu, and Hironori. Arakawa.   Ruthenium Sensitizers with a Hexylthiophene-Modified Terpyridine Ligand for Dye-Sensitized Solar Cells: Synthesis, Photo- and Electrochemical Properties, and Adsorption Behavior to the TiO2 Surface.   ACS Applied Materials & Interfaces 7, no.  (2015): 3152–61. https://doi.org/10.1021/am507442s.

6.) Rombouts, Frederik J. R., Gary Tresadern, Oscar Delgado, Carolina Martinez-Lamenca, Michiel Van Gool, Aranzazu Garcia-Molina, Sergio A. Alonso de Diego, et al.   1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads.   Journal of Medicinal Chemistry 58, no.  (2015): 8216–35. https://doi.org/10.1021/acs.jmedchem.5b01101.

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