Zn(II) Phthalocyanine tetrasulfonic acid

Zn(II) Phthalocyanine tetrasulfonic acid Mixture of regioisomers CAS: 61586-86-5 MDL: MFCD00672308

SDS

Molecular weight: 898.15 g/mol

Molecular Formula: C₃₂H₁₆N₈O₁₂S₄Zn  

CAS Number:  61586-86-5

Storage: Store at room temperature, protect from light.

Synonyms:   zinc phthalocyanine tetrasulfonate, zinc tetrasulfophthalocyanine, zinc tetrasulfophthalocyanine, tetrasodium salt, Zn-TSPC, ZnPcS4 

Fields of Interest: Photodynamic Therapy

Background: Zn(II) Phthalocyanine tetrasulfonic acid has been extensively investigated as an agent for photodynamic therapy due to emission in the near infrared region.

References:

1.) Sekkat, N., van den Bergh, H., Nyokong, T., Lange, N.; Like a Bolt from the Blue: Phthalocyanines in Biomedical Optics. Molecules 2012, 17, 98-144; https://doi.org/10.3390/molecules17010098

2.) Wang, J., Zhang, Y., Ye, J., Jiang, Z.; Enhanced fluorescence of tetrasulfonated zinc phthalocyanine by graphene quantum dots and its application in molecular sensing/imaging. Luminescence 2017, 32, 573-580. doi: 10.1002/bio.3223.

3.) Chekwube, A.E., George, B., Arahamse, H.; Phototoxic effectiveness of zinc phthalocyanine tetrasulfonic acid on MCF-7 cells with overexpressed p-glycoprotein. J Photochem Photobiol B. 2020 Mar;204:111811.doi: 10.1016/j.jphotobiol.2020.111811.

4.) Valduga, et al. Spectroscopic studies on Zn(II)-phthalocyanine in homogeneous and microheterogeneous systems. Journal of Inorganic Biochemistry Volume 29, Issue 1, January 1987, Pages 59-65. https://doi.org/10.1016/0162-0134(87)80012-0

5.) Attia, et al. Phthalocyanine photosensitizers as contrast agents for in vivophotoacoustic tumor imaging. Biomedical Optics Express Vol. 6, Issue 2, pp. 591-598 (2015). https://doi.org/10.1364/BOE.6.000591

6.) Zhang, et al. Recent applications of phthalocyanines and naphthalocyanines for imaging and therapy. https://doi.org/10.1002/wnan.1420