(R)-Tetrahydrofurfuryl Alcohol, aka THFA
Molecular Formula:  C5H10O2
CAS#:  22415-59-4Â
MDL:  MFCD03093085Â
Catalog#:  T36087Â
Molecular weight:  102.13 g/mol
Other names: Â
- THFA
- (R)-(Tetrahydrofuran-2-yl)methanol
- (oxolan-2-yl)methanol
- [(2R)-oxolan-2-yl]methanol
- (R)-Tetrahydrofurfuryl alcohol
Fields of Interest:  Organic synthesis, polymerization, epoxy resin formulations, agrochemical, coatings and stripping formulations
Background & Applications: Tetrahydrofurfuryl alcohol (THFA) consists of a tetrahydrofuran ring substituted in the 2-position with a hydroxymethyl group. This colorless liquid serves as a specialty solvent and a synthetic intermediate, for example, in the production of 3,4-dihydropyran. THFA is prepared by hydrogenation of furfural 1. Additionally, tetrahydrofurfuryl alcohol acts as a precursor to 1,5-pentanediol 2.
Here is a brief overview of some applications for tetrahydrofurfuryl alcohol (THFA):
- Epoxy Resins: THFA is often used in epoxy resin formulations in either the epoxy component or amine hardener as well as other general resin applications 3
- Solvent: Tetrahydrofurfuryl alcohol is used as a solvent in various chemical processes.
- Chemical Intermediary: THFA serves as an intermediate in the synthesis of other organic compounds.
- Polymerization: THFA can be used in polymerization reactions.
- Coating Industry: THFA finds applications in the coating/paint stripper formulations
- Other industries: THFA is often used as a solvent in the agrochemical industry (such as biocide & pesticide formulations) and in cleaning products
Appearance:  Clear, colorless oilÂ
Purity: 97%
Storage:  Store at 3-5 °C
Literature:
-  H. E. Hoydonckx; W. M. Van Rhijn; W. Van Rhijn; D. E. De Vos; P. A. Jacobs (2007). “Furfural and Derivatives”. Ullmann’s Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a12_119.pub2. ISBN 978-3527306732.
- Nakagawa, Yoshinao; Tomishige, Keiichi (2012). “Production of 1,5-Pentanediol from Biomass via Furfural and Tetrahydrofurfuryl Alcohol”. Catalysis Today. 195: 136–143. doi:10.1016/j.cattod.2012.04.048.
- “Natural Resins Products THFA”. SilvaTeam. 2022.