(R)-Tetrahydrofurfuryl Alcohol (THFA)

Catalog#:  T36087

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(R)-Tetrahydrofurfuryl Alcohol, aka THFA

Molecular Formula:  C5H10O2

CAS#:  22415-59-4 

MDL:  MFCD03093085 

Catalog#:  T36087 

Molecular weight:  102.13 g/mol

Other names:  

  • THFA
  • (R)-(Tetrahydrofuran-2-yl)methanol
  • (oxolan-2-yl)methanol
  • [(2R)-oxolan-2-yl]methanol
  • (R)-Tetrahydrofurfuryl alcohol

Fields of Interest:  Organic synthesis, polymerization, epoxy resin formulations, agrochemical, coatings and stripping formulations

Background & Applications: Tetrahydrofurfuryl alcohol (THFA) consists of a tetrahydrofuran ring substituted in the 2-position with a hydroxymethyl group. This colorless liquid serves as a specialty solvent and a synthetic intermediate, for example, in the production of 3,4-dihydropyran. THFA is prepared by hydrogenation of furfural 1. Additionally, tetrahydrofurfuryl alcohol acts as a precursor to 1,5-pentanediol 2.

Here is a brief overview of some applications for tetrahydrofurfuryl alcohol (THFA):

  • Epoxy Resins: THFA is often used in epoxy resin formulations in either the epoxy component or amine hardener as well as other general resin applications 3
  • Solvent: Tetrahydrofurfuryl alcohol is used as a solvent in various chemical processes.
  • Chemical Intermediary: THFA serves as an intermediate in the synthesis of other organic compounds.
  • Polymerization: THFA can be used in polymerization reactions.
  • Coating Industry: THFA finds applications in the coating/paint stripper formulations
  • Other industries: THFA is often used as a solvent in the agrochemical industry (such as biocide & pesticide formulations) and in cleaning products

Appearance:  Clear, colorless oil 

Purity: 97%

Storage:  Store at 3-5 °C

Literature:

  1.  H. E. Hoydonckx; W. M. Van Rhijn; W. Van Rhijn; D. E. De Vos; P. A. Jacobs (2007). “Furfural and Derivatives”. Ullmann’s Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a12_119.pub2. ISBN 978-3527306732.
  2. Nakagawa, Yoshinao; Tomishige, Keiichi (2012). “Production of 1,5-Pentanediol from Biomass via Furfural and Tetrahydrofurfuryl Alcohol”. Catalysis Today. 195: 136–143. doi:10.1016/j.cattod.2012.04.048.
  3. “Natural Resins Products THFA”. SilvaTeam. 2022.
CAS #

22415-59-4

Molecular Formula

C5H10O2

Molecular Weight

102.13

Categories

Building Blocks

Purity %

>97%

Scaffold/Subcategory

Alcohol, Furan

Smiles

C1CC(OC1)CO

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