Pt(II) Coproporphyrin I

Product Number: C40425; CAS Number: 90540-79-7



SKU: C40425 Category:

Pt(II) Coproporphyrin I CAS: 90540-79-7 MDL: MFCD32662381

Molecular weight: 847.77 g/mol

Molecular Formula: C36H36N4O8Pt

CAS Number: 90540-79-7

Storage: Store at room temperature, protect from light

Synonyms: Pt(II) Coproporphyrin I, 90540-79-7, MFCD32662381, PtCp

Field of Interest: Phosphorescent Oxygen Sensors, Natural Porphyrin Derivatives, phosphorescent metalloporphyrin labeling reagents

Background: Pt(II) Coproporphyrin I is a naturally derived porphyrin specialty chemical manufactured by Frontier Specialty Chemicals. Conjugation of Pt(II) Coproporphyrin I with oligoarginine peptides produced a conjugate useful for sensing intracellular O2.1 Pt(II) Coproporphyrin I was used to synthesize phosphorescent metalloporphyrin labeling reagents having an isothiocyanato reactive group.2 Pt(II) Coproporphyrin I conjugates where used as a homogeneous assay for cellular proteases.Pt(II) Coproporphyrin I derivatives are used as labels in time-resolved luminescence microscopy.4



1.) Dmitriev. et al. Cell-Penetrating Conjugates of Coproporphyrins with Oligoarginine Peptides: Rational Design and Application for Sensing Intracellular O2. Bioconjugate Chem. 2011, 22, 12, 2507–2518.

2.) Soini, et al. Preparation of monofunctional and phosphorescent palladium(II) and platinum(II) coproporphyrin labeling reagents. Journal of Porphyrins and Phthalocyanines. Vol. 05, No. 10, pp. 735-741 (2001).

3.) O’Riordan, et al. Homogeneous assays for cellular proteases employing the platinum(II)–coproporphyrin label and time-resolved phosphorescence. Analytical Biochemistry. Volume 342, Issue 1, 1 July 2005, Pages 111-119.

4.) Soini, et al. Phosphorescent metalloporphyrins as labels in time-resolved luminescence microscopy: Effect of mounting on emission intensity. Microscopy Research & Technique. Volume 58, Issue Special Issue: The Innervation of Bone 15 July 2002 Pages 125-131.

5.) Papkovsky, D.B., O’Riordan, T.C. Emerging Applications of Phosphorescent Metalloporphyrins. J Fluoresc 15, 569–584 (2005).




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