N-(3-aminopropyl)-2-pyrrolidinone

Catalog#: A35206

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Name: N-(3-aminopropyl)-2-pyrrolidinone 

Molecular Formula: C7H14N2O 

CAS#: 7663-77-6 

SMILES: O=C1N(CCCN)CCC1 

MDL#: MFCD00003201 

Catalog#: A35206 

Molecular weight: 142.2 g/mol 

Other names: 

  • 1-(3-Aminopropyl)-2-pyrrolidone

Fields of Interest: Organic Synthesis 

Background & Applications:

N-(3-aminopropyl)-2-pyrrolidinone is a bifunctional pyrrolidone derivative combining a polar lactam ring with a reactive primary amine. This structure gives it high water solubility, strong hydrogen-bonding capacity, and chemical reactivity, making it primarily useful as an intermediate rather than a finished product. Its design is related to common industrial pyrrolidones (e.g., NMP), but the added amine enables covalent bonding and further functionalization. It can also be used as a precursor for bioactive heterocycles and a building block for drug candidates.

Industrially, it is used mainly in polymer, resin, and coating applications as a reactive intermediate, adhesion promoter, or functional additive, where it improves polarity, compatibility, and surface adhesion. It also serves as a fine chemical and pharmaceutical intermediate, and in specialty formulations (including agrochemical additives) where enhanced solubility and reactivity are desired.

Appearance: Pale orange/yellow viscous liquid 

Purity: 96%

Storage: Room Temperature 

Solubility: Methylene chloride and most organic solvents 

Literature: Patent: WO2003/105779,2003,A2 

Categories

Building Blocks

Scaffold/Subcategory

Amines & Derivatives

CAS #

[7663-77-6]

Purity %

96%

Smiles

O=C1N(CCCN)CCC1

Molecular Weight

142.2

Molecular Formula

C7H14N2O

Functional Groups

Amine, Nitrogen Heterocycle

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