Name:Â N-(3-aminopropyl)-2-pyrrolidinoneÂ
Molecular Formula:Â C7H14N2OÂ
CAS#:Â 7663-77-6Â
SMILES:Â O=C1N(CCCN)CCC1Â
MDL#:Â MFCD00003201Â
Catalog#:Â A35206Â
Molecular weight:Â 142.2Â g/molÂ
Other names:Â
- 1-(3-Aminopropyl)-2-pyrrolidone
Fields of Interest:Â Organic SynthesisÂ
Background & Applications:
N-(3-aminopropyl)-2-pyrrolidinone is a bifunctional pyrrolidone derivative combining a polar lactam ring with a reactive primary amine. This structure gives it high water solubility, strong hydrogen-bonding capacity, and chemical reactivity, making it primarily useful as an intermediate rather than a finished product. Its design is related to common industrial pyrrolidones (e.g., NMP), but the added amine enables covalent bonding and further functionalization. It can also be used as a precursor for bioactive heterocycles and a building block for drug candidates.
Industrially, it is used mainly in polymer, resin, and coating applications as a reactive intermediate, adhesion promoter, or functional additive, where it improves polarity, compatibility, and surface adhesion. It also serves as a fine chemical and pharmaceutical intermediate, and in specialty formulations (including agrochemical additives) where enhanced solubility and reactivity are desired.
Appearance:Â Pale orange/yellow viscous liquidÂ
Purity:Â 96%
Storage:Â Room TemperatureÂ
Solubility:Â Methylene chloride and most organic solventsÂ
Literature:Â Patent: WO2003/105779,2003,A2Â