Mn(III) meso-Tetra(4-sulfonatophenyl)porphine chloride (acid form)

Mn(III) meso-Tetra(4-sulfonatophenyl)porphine chloride (acid form) 5,10,15,20-Tetrakis(4-sulfonatophenyl)-21H,23H-porphine, manganese (III) chloride CAS: 221176-50-7 MDL: MFCD00216662

SDS

Molecular weight: 1023.364 g/mol

Molecular Formula: C₄₄H₂₈ClMnN₄O₁₂S₄

CAS Number: 221176-50-7

Storage: Store at room temperature, protect from light

Synonyms: 90587-86-3, Chlor[4,4′,4”,4”’-(5,10,15,20-porphyrintetrayl-κ²N²¹,N²³)tetrabenzolsulfonato(2-)]mangan, Chloro[4,4′,4”,4”‘-(5,10,15,20-porphyrinetétrayl-κ²N²¹,N²³)tetrabenzènesulfonato(2-)]manganèse, Chloro[4,4′,4”,4”‘-(5,10,15,20-porphyrintetrayl-κ²N²¹,N²³)tetrabenzenesulfonato(2-)]manganese, Manganese, chloro[4,4′,4”,4”’-(21H,23H-porphine-5,10,15,20-tetrayl-κN²¹,κN²³)tetrakis[benzenesulfonato](2-)]-, MFCD00216662, 221176-50-7, 5,10,15,20-Tetrakis(4-sulfonatophenyl)-21H,23H-porphine manganese(III) chloride, 5,10,15,20-Tetrakis(4-sulfonatophenyl)-21H,23H-porphine, manganese (III) chloride, MN(III) meso-Tetra(4-sulfonatophenyl)porphine chloride, Mn(III) meso-Tetra(4-sulfonatophenyl)porphine chloride (acid form)

Field of Interest: Catalysis, Synthetic Porphyrins, Water Soluble Porphyrins, MRI Contrast Reagents, Nanomaterials

Background: Mn(III) meso-Tetra(4-sulfonatophenyl)porphine chloride is a synthetic porphyrin specialty chemical manufactured by Frontier Specialty Chemicals. Mn(III) meso-Tetra(4-sulfonatophenyl)porphine chloride has been investigated as a tumor selective MRI contrast agent.^1-4 Mn(III) meso-Tetra(4-sulfonatophenyl)porphine chloride has been used to construct porphyrin containing Nanomaterials.^5-6

References:

1.) Fiel, et al. Mechanism of the localization of manganese (III) mesotetra(4-sulfonatophenyl)porphine i in mice bearing L1210 tumors. Cancer Letters. Volume 40, Issue 1, May 1988, Pages 23-32. https://doi.org/10.1016/0304-3835(88)90258-3

2.) Schaefle, et al. NMR Paramagnetic Relaxation of the Spin 2 Complex Mn^IIITSPP:  A Unique Mechanism. J. Phys. Chem. A 2005, 109, 15, 3267–3275. https://doi.org/10.1021/jp046227o

3.) Cheng, et al. Complementary Strategies for Developing Gd-Free High-Field T₁ MRI Contrast Agents Based on Mn^III Porphyrins. J. Med. Chem. 2014, 57, 2, 516–520. https://doi.org/10.1021/jm401124b

4.) Lu, et al. Manganese(III) porphyrin oligomers as high-relaxivity MRI contrast agents. Bioorganic & Medicinal Chemistry. Volume 35, 1 April 2021, 116090. https://doi.org/10.1016/j.bmc.2021.116090

5.) Wang, et al. Porphyrin-Based Honeycomb Films and Their Antibacterial Activity. Langmuir 2014, 30, 22, 6419–6426. https://doi.org/10.1021/la501244s

6.) Koposova EA, Offenhäusser A, Ermolenko YE and Mourzina YG (2019) Photoresponsive Porphyrin Nanotubes of Meso-tetra(4-Sulfonatophenyl)Porphyrin and Sn(IV) meso-tetra(4-pyridyl)porphyrin. Front. Chem.7:351. doi: 10.3389/fchem.2019.00351