meso-Tetra(p-hydroxyphenyl)porphine

meso-Tetra(p-hydroxyphenyl)porphine 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine CAS: 51094-17-8 MDL: MFCD00191501

SDS

Molecular weight: 678.7 g/mol

Molecular Formula: C₄₄H₃₀N₄O₄

CAS Number: 51094-17-8

Storage: Store at room temperature, protect from light.

Synonyms: 51094-17-8, 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine, 5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin, 4,4′,4”,4”’-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-Phenol, 4-[10,15,20-tris(4-hydroxyphenyl)-21,23-dihydroporphyrin-5-yl]phenol, 4,4′,4”,4”’-(5,10,15,20-Porphyrinetétrayl)tetraphénol, 4,4′,4”,4”’-(5,10,15,20-Porphyrintetrayl)tetraphenol, 4,4′,4”,4”’-(5,10,15,20-Porphyrintetrayl)tetraphenol, 4,4′,4”,4”’-Porphyrin-5,10,15,20-tetrayltetraphenol, 5,10,15,20-tetrakis(4-hydroxyphenyl)-21H,23H-porphine, 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphyrin, 51094-17-8, MFCD00191501, Phenol, 4,4′,4”,4′”-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-, [51094-17-8], 4,4′,4”,4”’-(21H,23H-Porphine-5,10,15,20-tetrayl)tetrakis(phenol), 4,4′,4”,4”’-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-Phenol, 5,10,15,20-(tetra-4-hydroxyphenyl)porphyrin, 5,10,15,20-tetra(4-hydroxyphenyl)porphyrin, 5,10,15,20-TETRAKIS -21H,23H-PORPHINE,5,10,15,20-Tetrakis(4-hydroxyphenyl) porphyrin, 5,10,15,20-Tetrakis(4-hydroxyphenyl)porphine, 5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin, AC1OBGNM, ACMC-209krr, AG-F-72410, AGN-PC-0LQXW5, AGN-PC-0OBFX7, ANW-31189, BS-16931, CTK4J3624, meso-Tetra(p-hydroxyphenyl)porphine, para-tetrahydroxyphenylporphyrin, tetra-(4-hydroxyphenyl)porphin, VFHDWGAEEDVVPD-UHFFFAOYSA-N

Field of Interest: Photosensitizers, Photodynamic Therapy, Covalent Organic Frameworks

Background: meso-Tetra(p-hydroxyphenyl)porphine is a synthetic porphyrin that has been investigated as a photodynamic therapy agent^1,2,3. A PEGylated derivative of meso-tetra(p-hydroxyphenyl)porphine was used to functionalize silver nanoparticles with potential applications as theranostic and sensing agents⁴. Meso-tetra(p-hydroxyphenyl)porphine was used for the construction of a covalent organic framework for supercapacitor applications⁵.

References: 

1.) Berenbaum, M.C., Akande, S.L., Bonnett, R., Kaur, H., Ioannou, S., White, R.D., Winfield, U.J.; Meso-Tetra(hydroxyphenyl)porphyrins, a new class of potent tumor photosensitisers with favorable selectivity. British Journal of Cancer 1986, 54, 717-725. https://doi.org/10.1038/bjc.1986.232

2.) Berenbaum, M.C., Bonnett, R., Chevretton, E.B., Akande-Adebakin, S.L, Ruston, M.; Selectivity of meso-tetra(hydroxyphenyl)porphyrins and chlorins and of photofrin II in causing photodamage in tumour, skin, muscle, and bladder. The concept of cost-benefit in analysing the results. Lasers in Medical Science 1993,8, 235-243. https://doi.org/10.1007/BF02547845

3.) Wikene, K.O., Bruzell, E., Tonnesen, H.H; Improved antibacterial phototoxicity of a neutral porphyrin in natural deep eutectic solvents. Journal of Photochemistry and Photobiology B: Biology 2015, 148, 188-196. https://doi.org/10.1016/j.jphotobiol.2015.04.022

4.) Nicosia, A., Abbadessa, A., Vento, F., Mazzaglia, A., Mineo, P.G.; Silver Nanoparticles Decorated with PEGylated Porphyrins as Potential Theranostic and Sensing Agents. Materials 2021, 14, 2764. https://doi.org/10.3390/ma14112764

5.) Sajjad, M., Lu, W.; Covalent organic frameworks based nanomaterials: Design, synthesis, and current status for supercapacitor applications: A review. Journal of Energy Storage, 2021, 39, 102618. https://doi.org/10.1016/j.est.2021.102618