Ga(III) meso-Tetraphenylporphine chloride

Ga(III) meso-Tetraphenylporphine chloride CAS: 78833-52-0 MDL: MFCD32662380

Molecular weight: 717.90 g/mol

Molecular Formula: C₄₄H₂₈ClGaN₄

CAS Number: 78833-52-0

Storage: Store at room temperature, protect from light.

Synonyms: 21H,23H-Porphine, 5,10,15,20-tetraphenyl-, gallium salt, hydrochloride (1:1:1), Chlorure 5,10,15,20-tétraphénylporphine-21,23-diide de gallium (1:1:1), Gallium chloride 5,10,15,20-tetraphenylporphine-21,23-diide (1:1:1), Galliumchlorid-5,10,15,20-tetraphenylporphin-21,23-diid (1:1:1), 78833-52-0, MFCD32662380

Fields of Interest: Synthetic Porphyrins, Catalysis, Antimicrobial Porphyrins, Synthetic Heme Analogues

Background: Ga(III) meso-Tetraphenylporphine chloride is a synthetic porphyrin specialty chemical manufactured by Frontier Specialty Chemicals. Ga(III) meso-Tetraphenylporphine chloride display electrocatalytic properties towards the hydrogen evolution reaction.¹ Ga(III) meso-Tetraphenylporphine chloride has antimicrobial properties.² Ga(III) meso-Tetraphenylporphine chloride has been used as a synthetic heme analogue.^3,4 The spectroscopic and photophysical properties of Ga(III) meso-Tetraphenylporphine chloride have been reported.^5,6

References:

1.) Wang, et al. Electrocatalytic hydrogen evolution with gallium hydride and ligand-centered reduction. Chem. Sci., 2019,10, 2308-2314. https://doi.org/10.1039/C8SC05247F

2.) Choi, et al. In Vitro Efficacy of Free and Nanoparticle Formulations of Gallium(III) meso-Tetraphenylporphyrine against Mycobacterium avium and Mycobacterium abscessus and Gallium Biodistribution in Mice. Mol. Pharmaceutics 2018, 15, 3, 1215–1225. https://doi.org/10.1021/acs.molpharmaceut.7b01036

3.) DiPasquale, et al. Hydrogen Peroxide:  A Poor Ligand to Gallium Tetraphenylporphyrin. J. Am. Chem. Soc. 2008, 130, 6, 1812–1813. https://doi.org/10.1021/ja077598w

4.) Meininger, et al. Gallium(III) Tetraphenylporphyrinates Containing Hydrosulfide and Thiolate Ligands: Structural Models for Sulfur-Bound Iron(III) Hemes. Inorg. Chem. 2016, 55, 5, 2421–2426. https://doi.org/10.1021/acs.inorgchem.5b02822

5.) Ebeid, et al. Spectroscopic and stability characteristics of Ga-tetraphenyl porphyrin- and Ge- and Sn-tetra (p-methyl-phenyl) porphyrin chlorides. Spectrochimica Acta Part A: Molecular Spectroscopy. Volume 44, Issue 2, 1988, Pages 127-130. https://doi.org/10.1016/0584-8539(88)80235-6

6.) Ohno, et al. Luminescence of some metalloporphins including the complexes of the IIIb metal group. J. Chem. Phys. 82, 1779 (1985); https://doi.org/10.1063/1.448410