Chlorin e4

C40967-Chlorin e4 Technical Data Sheet


Product Number: C40967; CAS Number: 550-52-7



Chlorin e4 CAS: 550-52-7 MDL: MFCD10566749


Molecular weight: 552.7 g/mol

Molecular Formula: C33H36N4O4                              

CAS Number:  550-52-7

Storage: Store at –20 °C, protect from light.

Synonyms: SCHEMBL14039063, 21H,23H-PORPHINE-7-PROPANOIC ACID, 3-CARBOXY-13-ETHENYL-18-ETHYL-7,8-DIHYDRO-2,5,8,12,17-PENTAMETHYL-, (7S,8S)-, J2.069.722I, (7S,8S)-3-Carboxy-13-ethenyl-18-ethyl-7,8-dihydro-2,5,8,12,17-pentamethyl-21H,23H-porphyrin-7-propanoic acid.

Alternative Chemical Names

(17S,18S)-18-(2-Carboxyethyl)-7-ethyl-3,8,13,17,20-pentamethyl-12-vinyl-17,18-dihydro-2-porphyrincarbonsäure, (17S,18S)-18-(2-Carboxyethyl)-7-ethyl-3,8,13,17,20-pentamethyl-12-vinyl-17,18-dihydro-2-porphyrincarboxylic acid, 21H,23H-Porphine-7-propanoic acid, 3-carboxy-13-ethenyl-18-ethyl-7,8-dihydro-2,5,8,12,17-pentamethyl-, (7S,8S)-, Acide (17S,18S)-18-(2-carboxyéthyl)-7-éthyl-3,8,13,17,20-pentaméthyl-12-vinyl-17,18-dihydro-2-porphyrinecarboxylique, (7S,8S)-3-carboxy-13-ethenyl-18-ethyl-7,8-dihydro-2,5,8,12,17-pentamethyl-21H,23H-Porphine-7-propanoic acid, 21H,23H-Porphine-7-propanoic acid,3-carboxy-13-ethenyl-18-ethyl-7,8-dihydro-2,5,8,12,17-pentamethyl-,(7s,8s)-

Field of Interest: Natural Products Synthesis, Inflammation Activity, Solar Cells

Background: Chlorin e4 is a porphyrin based natural product and fine chemical that possesses photophysical properties while cytoprotective in mammalian cells. 1,2 This compound is found in chlorophyllin extracts, and may add to its chemoprevention properties, and have high membrane affinity compared to porphyrins.3, 4


1.) Wang, Xiao-Feng; Kitao, Osamu, Natural chlorophyll-related porphyrins and chlorins for dye-sensitized solar cells, Molecules (2012), 17, 4484-4497.

2.) Fahey Jed W; Stephenson Katherine K; Dinkova-Kostova Albena T; Egner Patricia A; Kensler Thomas W; Talalay Paul, Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes , Carcinogenesis (2005), 26(7), 1247-55.

3.) Egner, Patricia A.; Stansbury, Kevin H.; Snyder, Edward P.; Rogers, Mark E.; Hintz, Paul A.; Kensler, Thomas W., Identification and Characterization of Chlorin e4 Ethyl Ester in Sera of Individuals Participating in the Chlorophyllin Chemoprevention Trial, Chemical Research in Toxicology (2000), 13(9), 900-906.

4.)  Vermathen, Martina; Marzorati, Mattia; Bigler, Peter, Self-Assembling Properties of Porphyrinic Photosensitizers and Their Effect on Membrane Interactions Probed by NMR Spectroscopy,  Journal of Physical Chemistry B (2013), 117(23), 6990-7001.


Functional Groups

, , ,

Porphyrin Family

Chlorophyll Derivatives, Free Base Porphyrins

Porphyrin Substitution

Beta Substituted Porphyrins, Carboxy Substituted Porphyrins

Purity %


Molecular Formula


Molecular Weight




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