Biliverdin dimethyl ester

Product Number: B610-9; CAS Number: 10035-62-8

B610-9 Biliverdin dimethyl ester Technical Data Sheet 



SKU: B610-9 Category:

Biliverdin dimethyl ester CAS: 10035-62-8 MDL: MFCD08669552


Molecular weight: 610.70 g/mol

Molecular Formula: C35H38N4O6

CAS Number:  10035-62-8

Storage: Store at room temperature, protect from light.

Field of Interest: Heme Oxygenase pathway, Antioxidants, Small ultra red fluorescent protein (smURFP).


Biliverdin Dimethyl ester is a synthetic derivative of biliverdin, a waste product from the degradation of heme1. Reduction of biliverdin produces bilirubin, which is then excreted mainly as the gluconoride. Biliverdin is the pigment which is naturally found in green and blue bird egg shells2. Biliverdin Dimethyl ester is of interest as a chromophore in far-red fluorescent proteins which are being developed for bio-imaging3. Biliverdin Dimethyl Ester exhibits fluorescence maxima at 710 and 770 nm in ethanol at room temperature4. Novel ultra-red fluorescent protein smURFP can be used as a sensor for biliverdin in blood serum5. Biliverdin is thought to possess anti-oxidant properties in mammals, but the mode of action is unclear6.


1.) Sassa, S.; Biological Implications of Heme Metabolism. Journal of Clinical Biochemistry.2006, 38, 138- 155.

2.) Halepas, S., Hamchand, R., Lindeyer, S.E.D., Bruckner, C.; Isolation of Biliverdin IXa, as its Dimethyl Ester, from Emu Eggshells. J. Chem. Educ.2017, 94, 1533-1537.

3.) Liu, Y., Chen, Z., Wang, X., Cao, S., Xu, J., Jimenez, R., Chen, J.; Ultrafast spectroscopy of biliverdin dimethyl ester in solution: pathways of excited-state depopulation. Phys. Chem. Chem. Phys., 2020, 22, 19903-19912.

4.) Braslavsky, S.E., Holzwarth, A.R., Lehner, H., Schaffner, K.; The Fluorescence of biliverdin dimethyl ester. Helvetica Chimica Acta.,1978, 61, 2219-2222.

5.) Zhu, X., Feng, S., Jiang, Z., Zhang, H., Wang, Y., Yang, H., Wang, Z.; An ultra-red fluorescent biosensor for highly sensitive and rapid detection of biliverdin. Analytica Chimica Acta., Volume 1174, 22 August 2021, 338709.

6.) Dorazio, S.j., Halepas, S., Bruhn, T., Flaming, K.M., Zeller, M., Bruckner, C.; Singlet oxygen oxidation products of biliverdin IXa dimethyl ester. Bioorganic & Medicinal Chemistry.,2015,23, 7671-7675.


Functional Groups

, , , ,

Porphyrin Family

Bilirubin Derivatives, Linear Tetra-Pyrroles

Purity %


Molecular Formula


Molecular Weight



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