7-Bromo-1H-imidazo[1,2-a]pyridin-8-amine CAS: 1357945-44-8 MDL: MFCD22199338
Molecular weight: 212.05 g/mol
Molecular Formula: C7H6BrN3
CAS Number: 1357945-44-8
Storage: Store at 2-8 Co, under dry conditions.
Synonyms: 7-bromoimidazo[1,2-a]pyridin-8-amine, 1357945-44-8, imidazo[1,2-a]pyridin-8-amine,7-bromo-, 7-Bromo-1H-imidazo[1,2-a]pyridin-8-amine, SCHEMBL18137195
Uses: Synthesis building block, Organic Synthesis, imidazole-pyridine nitrogen heterocycle, synthesis, chlorine reactions
7-Bromo-1H-imidazo[1,2-a]pyridin-8-amine, is a synthetic fine chemical useful in the synthesis of pharmaceuticals and fine organic chemicals.
Selected References:
Balwe, Sandip Gangadhar, and Yeon Tae. Jeong. “An Approach towards the Synthesis of Novel Fused Nitrogen Tricyclic Heterocyclic Scaffolds via GBB Reaction.” Organic & Biomolecular Chemistry 16, (2018): 1287–96. https://doi.org/10.1039/C7OB02933K.
Israel, Mervyn, and Allan R. Day. “Preparation of Pyrido [2,3] Pyrazines, Pyrido[3,4]Pyrazines, and Imidazo[b]Pyridines.” Journal of Organic Chemistry 24, (1959): 1455–60. https://doi.org/10.1021/jo01092a018.
Saki, Mayumi, Hiroshi Tsumuki, Hiromi Nonaka, Junichi Shimada, and Michio. Ichimura. “KF26777 (2-(4-Bromophenyl)-7,8-Dihydro-4-Propyl-1H-Imidazo[2,1-i]Purin-5(4H)-Onedihydrochloride), a New Potent and Selective Adenosine A3 Receptor Antagonist.” European Journal of Pharmacology 444, (2002): 133–41. https://doi.org/10.1016/S0014-2999(02)01662-X.
Swanson, Devin M., Brad M. Savall, Kevin J. Coe, Freddy Schoetens, Tatiana Koudriakova, Judith Skaptason, Jessica Wall, et al. “Identification of (R)-(2-Chloro-3-(Trifluoromethyl)Phenyl)(1-(5-Fluoropyridin-2-Yl)-4-Methyl-6,7-Dihydro-1H-Imidazo[4,5-c]Pyridin-5(4H)-Yl)Methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 Receptor.” Journal of Medicinal Chemistry 59, (2016): 8535–48. https://doi.org/10.1021/acs.jmedchem.6b00989.