4,6-Dichloropyridin-3-ol

4,6-Dichloropyridin-3-ol CAS: 1196157-47-7 MDL: MFCD13190072

Molecular weight: 163.98    g/mol

Molecular Formula: C₅H₃Cl₂NO

CAS Number: 1196157-47-7

Storage: Store at 2-8 C^o, under dry conditions.

Synonyms:  None found.

Uses: Synthesis building block, Organic Synthesis, pyridine nitrogen heterocycle,  synthesis, chlorine reactions

4,6-Dichloropyridin-3-ol, is a synthetic specialty chemical useful in the synthesis of pharmaceuticals and specialty organic chemicals.

Selected References:

1.) Kudo, Noriaki, Mauro Perseghini, and Gregory C. Fu.   A Versatile Method for Suzuki Cross-Coupling Reactions of Nitrogen Heterocycles.   Angewandte Chemie, International Edition 45, no.   (2006): 1282–84. https://doi.org/10.1002/anie.200503479.

2.) Tu, Wangyang, Lei Liu, and Paul E. Floreancig.   Diastereoselective Tetrahydropyrone Synthesis through Transition-Metal-Free Oxidative Carbon-Hydrogen Bond Activation.   Angewandte Chemie, International Edition 47, no.   (2008): 4184–87. https://doi.org/10.1002/anie.200706002.

3.) Wang, Congyang, Souvik Rakshit, and Frank. Glorius.   Palladium-Catalyzed Intermolecular Decarboxylative Coupling of 2-Phenylbenzoic Acids with Alkynes via C-H and C-C Bond Activation.   Journal of the American Chemical Society 132, no.   (2010): 14006–8. https://doi.org/10.1021/ja106130r.

4.) Wang, Tao, Shuai Shi, Max M. Hansmann, Eva Rettenmeier, Matthias Rudolph, and A. Stephen K. Hashmi.   Synthesis of Highly Substituted 3-Formylfurans by a Gold(I)-Catalyzed Oxidation/1,2-Alkynyl Migration/Cyclization Cascade.   Angewandte Chemie, International Edition 53, no.   (2014): 3715–19. https://doi.org/10.1002/anie.201310146.

5.) Zhang, Rui, Wing-Yiu Yu, Tat-Shing Lai, and Chi-Ming. Che.   Enantioselective Hydroxylation of Benzylic C-H Bonds by D4-Symmetric Chiral Oxoruthenium Porphyrins.   Chemical Communications (Cambridge), no.   (1999): 1791–92. https://doi.org/10.1039/a904100a.

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