3-Bromo-4-(bromomethyl)benzaldehyde

Name: 3-Bromo-4-(bromomethyl)benzaldehyde 

Molecular Formula: C8H6Br2O

CAS#: 1189765-90-9

SMILES: BrC1=CC(C=O)=CC=C1CBr

MDL#: MFCD18390188

Catalog#: B36277

Molecular weight:  277.94 g/mol 

Other names: 

• None found

Fields of Interest:

• Pharmaceutical and medicinal chemistry

• Organic synthesis

• Fine chemicals and specialty chemicals

• Agrochemical intermediate research

• Process chemistry and route development

Background & Applications of 3-Bromo-4-(bromomethyl)benzaldehyde:

Background:

3-Bromo-4-(bromomethyl)benzaldehyde is a brominated aromatic aldehyde used as a versatile synthetic intermediate in pharmaceutical, agrochemical, and specialty chemical research, especially where bromomethyl and formyl functional groups enable further derivatization. This compound is an aromatic benzaldehyde derivative with both a formyl (-CHO) group and two bromine-containing substituents: one directly on the ring and one as a bromomethyl (-CH2Br) group. That combination makes it valuable in multistep organic synthesis because the aldehyde and bromomethyl groups can each be transformed selectively into more complex structures. Its listed molecular formula is C8H6Br2O, molecular weight 277.94, and CAS number 1189765-90-9.

Applications:
The main use of 3-Bromo-4-(bromomethyl)benzaldehyde is as a building block/intermediate rather than as a final commercial ingredient. Supplier and reference pages associate it with synthetic routes used in medicinal and fine chemical chemistry, where it can support formation of heterocycles, substituted benzyl derivatives, and other functionalized aromatic compounds.

Appearance: White crystalline solid 

Purity: 95%

Storage: -20 °C

Solubility: DCM, Diethyl ether, DMF

Literature:  

• Bioorganic and Medicinal Chemistry, 2021, vol. 29, art. no. 115871

• Journal of the American Chemical Society, 2009, vol. 131, # 39, p. 13908 – 13909