2-Formyl-5-hydroxypyridine 5-Hydroxy-2-pyridinecarboxaldehyde CAS: 31191-08-9 MDL: MFCD10697538
Molecular weight: 123.11 g/mol
Molecular Formula: C6H5NO2
CAS Number: 31191-08-9
Storage: Store at 2-8 Co, under dry conditions.
Synonyms: 5-hydroxypicolinaldehyde, 31191-08-9, 5-hydroxypyridine-2-carbaldehyde
5-Hydroxypyridine-2-carboxaldehyde, 5-HYDROXY-2-PYRIDINECARBOXALDEHYDE, 2-Formyl-5-hydroxypyridine, 2-Pyridinecarboxaldehyde, 5-hydroxy-, 5-hydroxy-2-formylpyridine, MFCD10697538, 5-HYDROXY-2-PYRIDINECARBALDEHYDE, NSC127948, Picolinaldehyde, dimer, 6-Formyl-3-pyridinol, 2-formyl-5-hydroxy pyridine, SCHEMBL179115
Uses: Synthesis building block, Organic Synthesis, pyridine nitrogen heterocycle, synthesis, aldehyde, formyl reactions
2-Formyl-5-hydroxypyridine, is a synthetic fine chemical useful in the synthesis of pharmaceuticals and fine organic chemicals.
Selected References:
Barman, Sanmitra, Katharine L. Diehl, and Eric V. Anslyn. The Effect of Alkylation, Protonation, and Hydroxyl Group Substitution on Reversible Alcohol and Water Addition to 2- and 4-Formyl Pyridine Derivatives. RSC Advances 4, (2014): 28893–900. https://doi.org/10.1039/C4RA03466J.
Blanz, Erwin J., Jr., and Frederic A. French. Carcinostatic Activity of 5-Hydroxy-2-Formylpyridine Thiosemicarbazone. Cancer Research 28, (1968): 2419–22.
Iaroshenko, Viktor O., Satenik Mkrtchyan, Gagik Ghazaryan, Ani Hakobyan, Aneela Maalik, Linda Supe, Alexander Villinger, et al. 3-(Dichloroacetyl)Chromone; a New Building Block for the Synthesis of Formylated Purine Isosteres: Design and Synthesis of Fused α-(Formyl)Pyridines. Synthesis, (2011): 469–79. https://doi.org/10.1055/s-0030-1258364.
Mukherjee, Kana M., T. N. Misra, and S. K. Nandy. Surface Enhanced Raman Spectroscopic Study of Isomeric Formyl Pyridines in Silver Colloid. Journal of Colloid and Interface Science 181, (1996): 413–21. https://doi.org/10.1006/jcis.1996.0398.
Queguiner, Guy, Michel Alas, and Paul. Pastour. 2-Formyl-3(and 4 and 5)-(Deuteroformyl)Pyridines and Their N-Oxides and 5-Deuteropyrido[2,3-d]Pyridazine. Comptes Rendus Des Seances de l’Academie Des Sciences, Serie C: Sciences Chimiques 268, (1969): 1531–34.
Queguiner, Guy, and Alain. Godard. Photochemical and Chemical Isomerization of 2,3- and 3,4- Diformyl-Pyridines and 2,3-Diformylquinoline. Comptes Rendus Des Seances de l’Academie Des Sciences, Serie C: Sciences Chimiques 269, (1969): 1646–49.
Queguiner, Guy, and Paul. Pastour. Synthesis in the Pyridine Series. V. Study of the Reduction of Ethyl Pyridinedicarboxylates. Bulletin de La Societe Chimique de France, (1969): 3678–83.


