2-Formyl-5-hydroxypyridine

2-Formyl-5-hydroxypyridine 5-Hydroxy-2-pyridinecarboxaldehyde CAS: 31191-08-9 MDL: MFCD10697538

Molecular weight:    123.11     g/mol

Molecular Formula: C₆H₅NO₂

CAS Number:  31191-08-9

Storage:               Store at 2-8 C^o, under dry conditions.

Synonyms:   5-hydroxypicolinaldehyde, 31191-08-9, 5-hydroxypyridine-2-carbaldehyde

5-Hydroxypyridine-2-carboxaldehyde, 5-HYDROXY-2-PYRIDINECARBOXALDEHYDE, 2-Formyl-5-hydroxypyridine, 2-Pyridinecarboxaldehyde, 5-hydroxy-, 5-hydroxy-2-formylpyridine, MFCD10697538, 5-HYDROXY-2-PYRIDINECARBALDEHYDE, NSC127948, Picolinaldehyde, dimer, 6-Formyl-3-pyridinol, 2-formyl-5-hydroxy pyridine, SCHEMBL179115

Uses:     Synthesis building block, Organic Synthesis, pyridine nitrogen heterocycle,  synthesis, aldehyde, formyl reactions

2-Formyl-5-hydroxypyridine, is a synthetic fine chemical useful in the synthesis of pharmaceuticals and fine organic chemicals.

Selected References:

Barman, Sanmitra, Katharine L. Diehl, and Eric V. Anslyn.    The Effect of Alkylation, Protonation, and Hydroxyl Group Substitution on Reversible Alcohol and Water Addition to 2- and 4-Formyl Pyridine Derivatives.    RSC Advances 4,   (2014): 28893–900. https://doi.org/10.1039/C4RA03466J.

 

Blanz, Erwin J., Jr., and Frederic A. French.    Carcinostatic Activity of 5-Hydroxy-2-Formylpyridine Thiosemicarbazone.    Cancer Research 28,   (1968): 2419–22.

 

Iaroshenko, Viktor O., Satenik Mkrtchyan, Gagik Ghazaryan, Ani Hakobyan, Aneela Maalik, Linda Supe, Alexander Villinger, et al.    3-(Dichloroacetyl)Chromone; a New Building Block for the Synthesis of Formylated Purine Isosteres: Design and Synthesis of Fused α-(Formyl)Pyridines.    Synthesis,   (2011): 469–79. https://doi.org/10.1055/s-0030-1258364.

 

Mukherjee, Kana M., T. N. Misra, and S. K. Nandy.    Surface Enhanced Raman Spectroscopic Study of Isomeric Formyl Pyridines in Silver Colloid.    Journal of Colloid and Interface Science 181,   (1996): 413–21. https://doi.org/10.1006/jcis.1996.0398.

 

Queguiner, Guy, Michel Alas, and Paul. Pastour.    2-Formyl-3(and 4 and 5)-(Deuteroformyl)Pyridines and Their N-Oxides and 5-Deuteropyrido[2,3-d]Pyridazine.    Comptes Rendus Des Seances de l’Academie Des Sciences, Serie C:  Sciences Chimiques 268,   (1969): 1531–34.

 

Queguiner, Guy, and Alain. Godard.    Photochemical and Chemical Isomerization of 2,3- and 3,4- Diformyl-Pyridines and 2,3-Diformylquinoline.    Comptes Rendus Des Seances de l’Academie Des Sciences, Serie C:  Sciences Chimiques 269,   (1969): 1646–49.

 

Queguiner, Guy, and Paul. Pastour.    Synthesis in the Pyridine Series.  V.  Study of the Reduction of Ethyl Pyridinedicarboxylates.    Bulletin de La Societe Chimique de France,   (1969): 3678–83.