1-Methyl-1H-Pyrazole-3-sulfonamide

1-Methyl-1H-Pyrazole-3-sulfonamide CAS: 88398-97-4 MDL: MFCD12547175

SDS

Molecular weight: 161.18 g/mol

Molecular Formula: C₄H₇N₃SO₂

CAS Number: 88398-97-4

Storage: Store at 2-8 C^o, under dry conditions.

Synonyms: None found

Uses: Synthesis building block, Organic Synthesis, pyrazole nitrogen heterocycle, synthesis, sulfonamide reactions

1-Methyl-1H-Pyrazole-3-sulfonamide, is a synthetic specialty chemical useful in the synthesis of pharmaceuticals and specialty organic chemicals.

Selected Patents and References:

1.) Preparation of sulfonylureas and related compounds as inhibitors of NLRP3 inflammasome activation for the treatment of diseases, O’Neill, Luke; Coll, Rebecca; Cooper, Matt; Robertson, Avril; Schroder, Kate, PCT Int. Appl. (2016), WO 2016131098 A1 20160825

2.) Preparation of novel heterocyclic compounds as bromodomain inhibitors,  Fish, Paul Vincent; Cook, Andrew Simon; Phillips, Christopher; Bent, Andrew Frank; Mills, James Edward John; Sciammetta, Nunzio, PCT Int. Appl. (2013), WO 2013027168 A1 20130228

3.) Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors, Liu, Xiaohua; Zhang, Yu; Huang, Wenjing; Tan, Wenfu; Zhang, Ao, & Medicinal Chemistry (2018), 26(2), 443-454. DOI:10.1016/j.bmc.2017.12.001

4.) Preparation of sulfonylureas and related compounds and use of same, O’Neill, Luke; Coll, Rebecca; Cooper, Matthew; Robertson, Avril; Schroder, Kate; MacLeod, Angus Murray; Miller, David John, PCT Int. Appl. (2017), WO 2017140778 A1 20170824

5.) Pyrazolesulfonylurea derivative and herbicide containing said derivative as active ingredient, Suzuki, Fumio; Iwasawa, Yoshihiro; Toshiaki, Sato; Ikai, Takasi; Oguti, Tosihiko, Eur. Pat. Appl. (1983), EP 87780 A2 19830907.