1-Ethylhydrazine hydrochloride

Product Number: E13445; CAS Number: 18413-14-4

E13445 Technical Data and Reactions


SKU: E13445 Category: Tag:

1-Ethylhydrazine hydrochloride CAS: 18413-14-4 MDL: MFCD01722460

Molecular weight:    96.56  g/mol

Molecular Formula: C2H9ClN2

CAS Number:  18413-14-4

Storage:               Store at 2-8 Co, under dry conditions.

Synonyms:  Ethylhydrazine hydrochloride, 18413-14-4, Hydrazine, ethyl-, monohydrochloride, 1-Ethylhydrazine hydrochloride, Ethylhydrazine.HCl

Uses:     Reactive reagent, protein labelling, active site labels, active site mapping, pyrazole synthesis, pharmaceutical synthesis, medicinal chemistry of  pyrazole

1-Ethylhydrazine hydrochloride, is a synthetic fine chemical useful for studying the biochemistry of macromolecules.

Selected References:

Aiello, E., S. Aiello, F. Mingoia, A. Bacchi, G. Pelizzi, C. Musiu, M. Giovanna Setzu, A. Pani, P. La Colla, and M. Elena Marongiu.   Synthesis and Antimicrobial Activity of New 3-(1-R-3(5)-Methyl-4-Nitroso-1H-5(3)-Pyrazolyl)-5-Methylisoxazoles.   Bioorganic & Medicinal Chemistry 8,  (2000): 2719–28. https://doi.org/10.1016/S0968-0896(00)00211-X.

Antonini, Ippolito, Paolo Polucci, Amelia Magnano, and Sante. Martelli.   Synthesis, Antitumor Cytotoxicity, and DNA-Binding of Novel N-5,2-Di(ω-Aminoalkyl)-2,6-Dihydropyrazolo[3,4,5-Kl]Acridine-5-Carboxamides.   Journal of Medicinal Chemistry 44,  (2001): 3329–33. https://doi.org/10.1021/jm010917o.


Ator, Mark A., Shantha K. David, and Paul R. Ortiz de Montellano.   Stabilized Isoporphyrin Intermediates in the Inactivation of Horseradish Peroxidase by Alkylhydrazines.   Journal of Biological Chemistry 264,  (1989): 9250–57.


Calle, Mariola, Luis A. Calvo, Alfonso Gonzalez-Ortega, and Ana M. Gonzalez-Nogal.   Silylated β-Enaminones as Precursors in the Regioselective Synthesis of Silyl Pyrazoles.   Tetrahedron 62,  (2006): 611–18. https://doi.org/10.1016/j.tet.2005.10.001.


Curran, Kevin J., Jeroen C. Verheijen, Joshua Kaplan, David J. Richard, Lourdes Toral-Barza, Irwin Hollander, Judy Lucas, Semiramis Ayral-Kaloustian, Ker Yu, and Arie. Zask.   Pyrazolopyrimidines as Highly Potent and Selective, ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin (MTOR): Optimization of the 1-Substituent.   Bioorganic & Medicinal Chemistry Letters 20,  (2010): 1440–44. https://doi.org/10.1016/j.bmcl.2009.12.086.


McLeod, Matt, Nicolas Boudreault, and Yves. Leblanc.   Synthetic Application of Monoprotected Hydrazines toward the Synthesis of 1-Aminopyrroles.   Journal of Organic Chemistry 61,  (1996): 1180–83. https://doi.org/10.1021/JO9518260.


Steffan, Robert J., Edward Matelan, Mark A. Ashwell, William J. Moore, William R. Solvibile, Eugene Trybulski, Christopher C. Chadwick, et al.   Synthesis and Activity of Substituted 4-(Indazol-3-Yl)Phenols as Pathway-Selective Estrogen Receptor Ligands Useful in the Treatment of Rheumatoid Arthritis.   Journal of Medicinal Chemistry 47,  (2004): 6435–38. https://doi.org/10.1021/jm049194+.


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