1-Boc-3-trifluoromethylpyrazole-5-boronic acid
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B11090 Technical Data Sheet and ReactionsÂ
Molecular weight: 280.4 g/mol
Molecular Formula: C9H12BF3N2O4
CAS Number: 1684433-60-0
Storage: Store at 2-8 Co, under dry conditions.
Synonyms: None found
Uses: Synthesis building block, Organic Synthesis, pyrazone, organofluorine
1-Boc-3-trifluoromethylpyrazole-5-boronic acid is a synthetic fine chemical useful in the synthesis of pharmaceuticals and fine organic chemicals.
Boronic Acid Derivative Coupling Reactions
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Billingsley, Kelvin L., Kevin W. Anderson, and Stephen L. Buchwald.   A Highly Active Catalyst for Suzuki-Miyaura Cross-Coupling Reactions of Heteroaryl Compounds.  Angewandte Chemie, International Edition 45, no.  (2006): 3484–88. https://doi.org/10.1002/anie.200600493.
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Kataoka, Noriyasu, Quinetta Shelby, James P. Stambuli, and John F. Hartwig.   Air Stable, Sterically Hindered Ferrocenyl Dialkylphosphines for Palladium-Catalyzed C-C, C-N, and C-O Bond-Forming Cross-Couplings.  Journal of Organic Chemistry 67, no.  (2002): 5553–66. https://doi.org/10.1021/jo025732j.
Kinzel, Tom, Yong Zhang, and Stephen L. Buchwald.   A New Palladium Precatalyst Allows for the Fast Suzuki-Miyaura Coupling Reactions of Unstable Polyfluorophenyl and 2-Heteroaryl Boronic Acids.  Journal of the American Chemical Society 132, no.  (2010): 14073–75. https://doi.org/10.1021/ja1073799.
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Tsuboyama, Akira, Hironobu Iwawaki, Manabu Furugori, Taihei Mukaide, Jun Kamatani, Satoshi Igawa, Takashi Moriyama, et al.   Homoleptic Cyclometalated Iridium Complexes with Highly Efficient Red Phosphorescence and Application to Organic Light-Emitting Diode.  Journal of the American Chemical Society 125, no.  (2003): 12971–79. https://doi.org/10.1021/ja034732d.
Wang, Dong-Hui, Masayuki Wasa, Ramesh Giri, and Jin-Quan. Yu.   Pd(II)-Catalyzed Cross-Coupling of Sp3 C-H Bonds with Sp2 and Sp3 Boronic Acids Using Air as the Oxidant.  Journal of the American Chemical Society 130, no.  (2008): 7190–91. https://doi.org/10.1021/ja801355s.
Wright, Stephen W., David L. Hageman, and Lester D. McClure.   Fluoride-Mediated Boronic Acid Coupling Reactions.  Journal of Organic Chemistry 59, no.  (1994): 6095–97. https://doi.org/10.1021/jo00099a049.
Yang, Shang-Dong, Chang-Liang Sun, Zhao Fang, Bi-Jie Li, Yi-Zhou Li, and Zhang-Jie. Shi.   Palladium-Catalyzed Direct Arylation of (Hetero)Arenes with Aryl Boronic Acids.  Angewandte Chemie, International Edition 47, no.  (2008): 1473–76. https://doi.org/10.1002/anie.200704619.
Yin, Jingjun, and Stephen L. Buchwald.   A Catalytic Asymmetric Suzuki Coupling for the Synthesis of Axially Chiral Biaryl Compounds.  Journal of the American Chemical Society 122, no.  (2000): 12051–52. https://doi.org/10.1021/ja005622z.
Zhang, Chunming, Jinkun Huang, Mark L. Trudell, and Steven P. Nolan.   Palladium-Imidazol-2-Ylidene Complexes as Catalysts for Facile and Efficient Suzuki Cross-Coupling Reactions of Aryl Chlorides with Arylboronic Acids.  Journal of Organic Chemistry 64, no.  (1999): 3804–5. https://doi.org/10.1021/JO990554O.